We investigate the Coulomb excitation of low-lying states of unstable nuclei in intermediate energy collisions (). It is shown that the cross sections for the E1 and E2 transitions are larger at lower energies, much less than 10 MeV/nucleon. Retardation effects and Coulomb distortion are found to be both relevant for energies as low as 10 MeV/nucleon and as high as 500 MeV/nucleon. Implications for studies at radioactive beam facilities are discussed.