Production en routine par cyclotron de fluor-18 et potassium-43 à usage médical au moyen d'une cible gazeuse télécommandée

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Abstract

In order to routinely produce high sterile activities of 18F and 43K for medical use, an electrically remote-controlled and versatile gaseous target has been designed for the preparation of both nuclides. This static Ne or Ar gas target system gives the following production rates: 20 mC of 18F/μA·h at 10.6 MeV and more than 60 μC of 43K/μA·h at 21.0 MeV.

In a production run of 200 mC (18F) and 3 mC (43K) the maximum handling dose never reaches more than 5 mR (finger dose) which means considerable reduction of radiation dose and absence of health hazard of such a procedure. This target system can also be used in a dynamic mode now under investigation for the labelling of organic compounds in organic liquid solvent or gaseous phase.

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